Transcranial / Intranasal Light Therapy: VieLight Neuro Wearable Brain Photobiomodulation Device

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Product Description

If you’re not familiar with the term “photomedicine”, then you will be soon, because one of the most cutting-edge features of the future of medicine and performance-enhancing biohacking involves the use of light and lightwaves (also known as “photobiomodulation”) for everything from nitric oxide release for physical and mental performance, to amplifying blood flow to the brain, to enhancing cognitive, muscular and mental performance, to building new red blood cells and optimizing oxygenation and far, far more.

For example, intranasal light therapy, which Ben Greenfield first introduced to the world in his podcast “How To Use Low Level Light Therapy and Intranasal Light Therapy For Athletic Performance, Cognitive Enhancement & More“, is literally light stimulation of blood capillaries in the nasal cavity and head. It has been used for the past couple decades as a very non-invasive method to introduce therapeutic light energy into the human body, and there’s actually a surprising amount of research (more details below) on this form of non-ionizing radiation on biological systems, including effects on cognitive performance, fighting free radicals, combatting Alzheimer’s symptoms and more.

This form of photobiomodulation used to be something you could only find in a hospital or expensive clinical setting, but it can now be delivered via an extremely affordable headset device called the VieLight. You can click here to peruse the VieLight models now (use code GREENFIELD for 10% off) or just keep reading for the nitty-gritty science and details behind how photomedicine works.


What Is Photobiology?

Let’s begin with photobiology, because to understand photobiomodulation and photomedicine, you must first grasp the concept of photobiology.

Photobiology is simply the study of the effects of non-ionizing radiation on biological systems. The biological effect varies with the wavelength region of the radiation (in this case “radiation” is not a bad term, but rather a completely natural phenomenon, similar to sunlight). The radiation is absorbed by molecules in skin such as DNA, protein or certain drugs. The molecules are changed chemically into products that initiate biochemical responses in the cells.

Biological reaction to light is nothing new or unnatural, and there are numerous examples of light induced photochemical reactions in biological systems. Vitamin D synthesis in our skin is an example of a photochemical reaction. The power density of sunlight is only 105 mW/cm2 yet when ultraviolet B (UVB) rays strikes our skin, it converts a universally present form of cholesterol, 7-dehydrocholesterol to vitamin D3. We normally experience this through our eyes which are obviously photosensitive – our vision is based upon light hitting our retinas and creating a chemical reaction that allows us to see. Throughout the course of human and plant history, photons have played a vital role in photo-chemically energizing certain cells.

At the cellular level, visible red and near infrared light energy stimulates cells to generate more energy and undergo self-repair. Each cell has mitochondria, which perform the function of producing cellular energy called “ATP”. This production process involves the respiratory chain. A mitochondrial enzyme called cytochrome oxidase c then accepts photonic energy when functioning below par.

Now here’s where things get really important, because the actual wavelength of light is crucial.


How To Get The Right Wavelengths To Get The Photomedicine Effect

For decades, scientists in Russia, parts of Eastern Europe and China researched the effects of light energy of specific wavelengths and power density on blood, in everyday people and athletes. They discovered that light energy has positive modulating effects on red blood cells, optimizing their cellular structure and oxygenation capacity. Additionally, photobiomodulation may stimulate mitochondria within white blood cells, potentially leading to an enhanced immune system.

And that’s not all.

Electromagnetic radiation within the 633-655nm wavelength is ideal for blood photobiomodulation, due to the higher degree of scattering and absorption by blood and water and energy density. This is because each photon contains a certain amount of energy. The different types of radiation are defined by the the amount of energy contained in the photons. Red photons are ideal due to their relatively lower energy density and higher absorption coefficient. On the other hand, blue photons contain sufficient energy to kill bacteria and activate photosensitizers – while, UV photons have the ability to destroy and alter DNA cellular structure upon prolonged exposure. This same wavelength can also be used to boost oxygenation, because the improved cellular erythrocyte structure in response to this light augments the oxygenation capacity of your circulatory system.

In recent years, the ability of mammalian mitochondria to capture photonic energy and produce ATP has been studied. The correct wavelength for the target cells or chromophores must be employed (633-810 nm). If the wavelength is incorrect, optimum absorption will not occur and as the first law of photobiology states, the Grotthus-Draper law, without absorption there can be no reaction.

The photon intensity, i.e., spectral irradiance or power density (W/cm2), must be adequate, or once again absorption of the photons will not be sufficient to achieve the desired result. If the intensity is too high, however, the photon energy will be transformed to excessive heat in the target tissue, and that is undesirable.

Finally, the dose or fluence must also be adequate (J/cm2), but if the power density is too low, then prolonging the irradiation time to achieve the ideal energy density or dose will most likely not give an adequate final result, because the Bunsen-Roscoe law of reciprocity, the 2nd law of photobiology, does not hold true for low incident power densities.

Near-infrared light stimulates mitochondrial respiration in neurons by donating photons that are absorbed by cytochrome oxidase, a bioenergetics process called photoneuromodulation in nervous tissue. The absorption of luminous energy by the enzyme results in increased brain cytochrome oxidase enzymatic activity and oxygen consumption. Since the enzymatic reaction catalyzed by cytochrome oxidase is the reduction of oxygen to water, acceleration of cytochrome oxidase catalytic activity directly causes an increase in cellular oxygen consumption. Increased oxygen consumption by nerve cells is coupled to oxidative phosphorylation, ATP production increases as a consequence of the metabolic action of near-infrared light. This type of luminous energy can enter brain mitochondria transcranially, and—independently of the electrons derived from food substrates—it can directly photostimulate cytochrome oxidase activity.


How The VieLight Works

So how does brain photobiomodulation using a device like the VieLight actually work? Here’s an excerpt from Mechanisms of Brain Photobiomodulation (Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6): 3439–3444.)

“Low-energy photon irradiation in the near-IR spectral range with low-energy lasers or LEDs positively modulates various important biological processes in cell culture and animal models. Photobiomodulation is applied clinically in the treatment of soft tissue injuries and accelerated wound healing. The mechanism of photobiomodulation by red to near-IR light at the cellular level has been ascribed by research institutions to the activation of cellular mitochondrial respiratory chain components, resulting in a signaling cascade that promotes cellular proliferation and cytoprotection.

Research indicates that cytochrome c oxidase is a key photo-acceptor of irradiation in the far-red to near-IR spectral range. Cytochrome c oxidase is an integral membrane protein that contains multiple redox active metal centers and has a strong absorbency in the far-red to near-IR spectral range detectable in-vivo by near-IR spectroscopy.

Additionally, photobiomodulation increases the rate of electron transfer in purified cytochrome oxidase, increasing mitochondrial respiration and ATP synthesis in isolated mitochondria, and up-regulating cytochrome oxidase activity in cultured neuronal cells – leading to neuroprotective effects and neuronal function.

In addition to increased oxidative metabolism, red to near-IR light stimulation of mitochondrial electron transfer is known to increase the generation of reactive oxygen species (ROS). ROS functions as signaling molecules, providing communication between mitochondria and the nucleus.”

There are several mechanisms associated with promoting physiological change through this type of photobiomodulation therapy (PBMT). The wavelengths primarily used with PBM is within the near-infrared range of the electromagnetic spectrum with a sufficient power density. When hypoxic/impaired cells are irradiated with low level NIR photons, there is increased mitochondrial adenosine tri-phosphate (ATP) production within their mitochondria. Another change is the release of nitric oxide from the hypoxic/impaired cells. Neurons are cells that contain mitochondria and nitric oxide.

In hypoxic neuronal cells, cytochrome-C oxidase (CCO), a membrane-bound protein that serves as the end-point electron acceptor in the cell respiration electron transport chain, becomes inhibited by non-covalent binding of nitric oxide. When exposed to NIR photons, the CCO releases nitric oxide, which then diffuses outs of the cell – increasing local blood flow and vasodilation.

Following initial exposure to the NIR photons, there is a brief burst of reactive oxygen species (ROS) in the neuron cell, and this activates a number of signaling pathways. The ROS leads to activation of redox-sensitive genes, and related transcription factors including NF-κβ. The PBMT stimulates gene expression for cellular proliferation, migration, and the production of anti-inflammatory cytokines and growth factors.

In a nutshell, this all means that you can use photobiomodulation to deliver massive amounts of blood flow and nitric oxide to your brain, fix mitochondria in neural tissue, deliver more blood flow to the rest of your body, decrease risk of brain degradation in the case of disease such as Alzheimer’s, and even enhance cognitive function and both physical and mental performance.

And you can now use the VieLight Neuro Alpha or the VieLight Neuro Gamma to get these effects via an easy-to-use, single-button headset device.


The VieLight Neuro Models

The VieLight Neuro Alpha and Neuro Gamma are next-generation transcranial-intranasal brain photobiomodulation headsets, with varying pulse frequencies. These devices utilize state-of-the-art microchip technology to boost photonic 810nm power density within the transcranial clusters, reaching 300% of the power output of the original Neuro. Their engineering team has downsized equivalent technology into the intranasal diode. Each session is auto-timed for 20 minutes, resulting in specific total irradiation with near-infrared photons of sufficient power density per cycle.

So what’s the difference between the two? In the VieLight Neuro Alpha, a 10 Hz pulse rate correlates with alpha brainwave oscillations and overall enhanced cellular light absorption for overall neuronal photobiomodulation. In the VieLight Neuro Gamma, a 40 Hz pulse rate correlates with gamma brainwave oscillations and specifically, enhanced memory function and cognition.

There’s actually even a smaller version too, the VieLight 810, which is designed for intranasal use only, rather than full head photomedicine. The VieLight 810 is a non-laser intranasal brain photobiomodulation device. The gentler brain stimulation (relative to the Neuro) is engineered for everyday use. The 810 nm power density capacity of its intranasal diode is approximately 33% of the VieLight Neuro. Each session is auto-timed for 25 minutes.

Every VieLight photobiomodulation devices combines solid state technology along with intranasal diodes built from transparent high-impact polycarbonate to ensure quality and durability – turning this into a lifetime investment. All VieLight Devices also come with a 6-month satisfaction guarantee.

If you’re ready to…
  • Increase blood flow to the brain and body
  • Increase nitric oxide levels
  • Boost oxygenation for physical or mental performance
  • Enhance memory function and cognition
  • Shut down inflammation in the brain
  • And much more…

More Resources & Studies

General Photobiomodulation Explained
Brain Photobiomodulation Explained
Systemic Photobiomodulation Explained
Vielight Clinical Studies
Vielight References
MIT study on visual exposure to 40Hz Gamma light

Additional information

Servings per box

30

What are the ingredients?

Our sleep product is simply very small amounts of the nutrients involved in the production of melatonin: L-tryptophan, 5HTP, Vitamin D3, Magnesium, and a very small dose of melatonin. Since an increase in brain GABA levels, is also a normal player in the initiation of sleep, we have also included a small amount of a GABA derivative that can cross into the brain–called “phGABA”. The quantities of each ingredient are intended to replenish normal levels of these nutrients, to allow for the normal production of melatonin, and to help initiate the initial cascade of events that lead to deep, natural sleep.

How does it work?

Doc Parsley’s Sleep Remedy is designed to restore commonly deficient nutrients associated with sleep. In Dr. Parsley’s experience, once these nutrients have been restored to optimal levels, most people have vastly improved sleep. Your body is still doing all the work. We are just giving your body the materials it needs to create great sleep.

Can I take it if I’ve drank alcohol?

Alcohol is a central nervous system depressant. Drinking alcohol in excess is known to affect the brain regions that control sleep. If you have consumed excessive amounts of alcohol, we do not recommend using the sleep product. However, moderate to light alcohol consumption (one to two drinks) should be balanced with drinking more water, and should not negatively impact the effectiveness of the sleep supplement.

Does it have the drowsy side effects?

Because we are not aiming to trick your body’s normal physiology, the common side effects associated with sleep aids are unlikely. The side effects of many sleep aids are caused because the medication is mimicking or blocking a normal process in the body or brain. Our formulation is not designed to mimic or trick—just provide your body with the resources to do its natural processes.

The directions say 8 oz. of warm water, can I mix it with cold water?

The design of the product is to be a night-time treat, and part of a sleep ritual. Warm cups of nice tasting drinks are great for this. However, the product can be dissolved in any temperature water. The temperature of the water will not effect how the product works. However, it will dissolve more easily in warmer water, but it will taste less sweet in cool water.

Is it safe to give to my child?

This product has not been tested on children. It is not recommended for individuals under the age of 18.

How often should I take it?

If you routinely do not get enough sleep. I recommend taking this product every night. If you are trying to catch-up on sleep, after being sleep deprived, I recommend taking the supplement every night, until you have caught up. The product can also be used for jet-lag. In that case it would be taken for a duration related to how many time zones you are crossing.

Will it make me feel hungover?

The nutrients of the Sleep Remedy are all normally found in your body—and designed to create “normal” or optimal levels of these nutrients. This is not a physiological trick. Since your body and brain are creating sleep in a natural way, groggy or hung-over feelings are highly unlikely.

Can I take more than one?

If you have taken sleep drugs, anti-depressants, or anti-anxiety medications for a long period of time, you may feel somewhat resistant to the Sleep Remedy. Since the dosages of all ingredients within the Sleep Remedy are very low, taking 1.5-2.0 packets is unlikely to have negative consequences to those that feel the need for this. However, always start with the recommended dosage. If you feel like you need to increase the dose, do it very slowly. Remember that too much magnesium can cause diarrhea, and our product does have magnesium in it.

Will I still be able to wake up for my child?

Many sleep aides actually render the user “unconscious.” It is difficult, and possibly impossible to wake from this state. However, our Sleep Remedy is simply designed to help your body create normal, restful sleep. During normal sleep, most people are able to wake easily when their environment changes (crying baby, alarms, and things that go bump in the night).

Is it OK for everyday use?

You cannot build dependency on this product. You will not experience withdrawal symptoms. You can use normal doses for 1, 5, 50, 150, 500 days in a row, and the only thing that may build up in your system would be the vitamin D3, but depending on how much sunlight you get, and if you already supplement with D3 this is also unlikely. One final Vitamin D3 comment: taking Vitamin D3 at night will not cause insomnia. This is a common, but completely untrue misconception.

Will this inhibit normal production of melatonin?

Absolutely not. Our dosage is well below the level that would cause that. You would need at least 600% more melatonin than we use, and probably twice that. Melatonin is instrumental in helping us coordinate our circadian rhythms. L-tryptophan, 5HTP, Magnesium, Vitamin D3 are all required to make melatonin. Once melatonin levels start going up, your brain produces and releases a neurotransmitter called GABA. GABA helps slow down your neocortex – that big wrinkly bit that separates us from the rest of the animal kingdom. That is why we this product has the final ingredient phGABA. Since GABA can’t get into the brain very easily, some tricky biochemist figured out a way to get it into the brain by adding the “ph” part—which is a non-polar ring. That allows the GABA to cross into the brain.

Why is it a powder?

This product was originally designed with the Department of Defense (DOD), Navy SEALs, frequent red-eye flyers, shift-workers, and first responders in mind. It is easy to carry around, it will last 52 forevers on the shelf, it takes up very little room, in other words, it’s handy and neat. But, it is also designed to be a powder for a very important reason: bio-availability. If you take a bunch of different pills, some are pressed, some have a glycerin shell, some have a gelatin shell etc. They dissolve slowly, unreliably, and at different rates. This product is designed so that you can get all of the ingredients immediately, and at the same time.

Can you take it in the middle of the night?

If you wake up in the middle of the night, just take the product again. You can also split it: take half when you are going to bed, and take the other half when you wake up in the middle of the night. If you have no problem going to sleep, don’t take it before bed, just take it when you wake up in the middle of the night, and then lay back down, and breathe/relax/meditate etc.

Can I or should I combine this with anything?

Ben Greenfield's favorite one-two combo for sleep is a single packet of sleep remedy combined with 2-3 capsules of NatureCBD.

1 review for Transcranial / Intranasal Light Therapy: VieLight Neuro Wearable Brain Photobiomodulation Device

  1. Rated 5 out of 5

    Jad

    Whats the difference between this and EEG or a TCDS

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